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H P S

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial.
Lancet. 2003 Jun 14;361(9374):2005-16.

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M I R A C L

High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study.
Circulation. 2003 Sep 30;108(13):1560-6.

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V A H I T

Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group.
N Engl J Med. 1999 Aug 5;341(6):410-8.

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P R O S P E R

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial.
Lancet. 2002 Nov 23;360(9346):1623-30.

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A L L H A T

Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).
JAMA. 2002 Dec 18;288(23):2998-3007.

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L I F E

Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.
Lancet. 2002 Mar 23;359(9311):995-1003.

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4 S

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
Lancet. 1994 Nov 19;344(8934):1383-9.

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W O S C O P S

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group.
N Engl J Med. 1995 Nov 16;333(20):1301-7.

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C A R E

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators.
N Engl J Med. 1996 Oct 3;335(14):1001-9.

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A F C A P S / T e x C A P S

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study.
JAMA. 1998 May 27;279(20):1615-22.

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L I P I D S

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group.
N Engl J Med. 1998 Nov 5;339(19):1349-57.

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A V E R T

Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. Atorvastatin versus Revascularization Treatment Investigators.
N Engl J Med. 1999 Jul 8;341(2):70-6.

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